Drugs with Adverse Reactions

 

What is Adverse drug reactions,
Adverse drug reactions (ADRs), defined as ‘the unwanted effects of drugs occurring under normal conditions of use’, are a significant cause of morbidity and mortality. Around 5% of acute medical emergencies are
 dmitted with ADRs, and around 10–20% of hospital inpatients suffer an ADR during their stay. Unwanted effects of drugs are five to six times more likely in the elderly than in young adults; and the risk of an ADR rises sharply with
the number of drugs administered.
Look at the following Drugs and their Adverse Reactions.

 

Examples of adverse drug reactions
Type of reaction and drug             Adverse reaction
Type A (augmented)
ACE
inhibitors
Hypotension
Chronic cough
ACE
antagonists
Hypotension
Anticoagulants
Gastrointestinal
bleeding
Intracerebral
haemorrhage
Antipsychotics
Acute
dystonia/dyskinesia
Parkinsonian
symptoms
Tardive
dyskinesia
Cytotoxic
agents
Bone marrow
dyscrasias
Cancer
Erythromycin
Nausea,
vomiting
Glucocorticosteroids
Hypoadrenalism
Osteoporosis
Insulin
Hypoglycaemia
Tricyclic
antidepressants
Dry mouth
Type B (bizarre)
Benzylpenicillin
Radiological contrast media
Anaphylaxis
Broad-spectrum
penicillins
Maculopapular
rash
Carbamazepine
Lamotrigine
Phenytoin
Sulphonamides
Toxic
epidermal
necrolysis
Stevens–Johnson
syndrome
Carbamazepine
Diclofenac
Isoniazid
Phenytoin
Rifampicin
Hepatotoxicity
Isotretinoin
SSRIsa
Depression
Suicidal
ideation
 
 
 
 
 
 
 
 
 
 
 
 
 
 
 

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