NAPLEX Practice Question # 102

NAPLEX Quiz.

Practice Question # 102.


Naplex

aspirin-side-effects

 

 

NSAIDs, except aspirin, exert their anti-inflammatory effect by a competitive and reversible active site inhibition of COX. Aspirin irreversibly inhibits COX by covalent acetylation of the enzyme. The inhibition of COX reduces the local synthesis of PGs that include pro-inflamatory actions among the diverse physiological role for the PGs (see section II). The PG family is also associated with fever and the perception of pain that accounts for the antipyretic and analgesic effects of the NSAIDs.

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