NCLEX RN Practice Question # 784

NCLEX Examination.

Practice Question # 784.

 

nclex examination

 

Vancomycin:

Vancomycin hydrochloride is used increasingly to treat methicillin-resistant S. aureus, which has become a major concern in the United States and other parts of the world. Because of the emergence of vancomycin-resistant enterococci, vancomycin must be used judiciously. As a rule of thumb, it should be used only when culture and sensitivity test results confirm the need for it.

Pharmacokinetics:

Because vancomycin is absorbed poorly from the GI tract, it must be given IV to treat systemic infections. An oral form of vancomycin is used to treat pseudomembranous colitis. Remember, however, that IV vancomycin can’t be used in place of oral vancomycin and vice versa. The two forms aren’t interchangeable.

 

Adverse reactions:

Adverse reactions to vancomycin, although rare, include:

  • Hypersensitivity and anaphylactic reactions
  • Drug fever
  • Eosinophilia
  • Neutropenia (reduced number of neutrophils, a type of WBC)
  • Hearing loss (transient or permanent), especially in excessive doses, such as when it’s given with other ototoxic drugs
  • Nephrotoxicity
  • Red man syndrome.

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