Practice Question # 796.
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What causes Renal Calculi:
Renal calculi may result from several causes:
- Decreased urine production from dehydration concentrates calculus-forming substances.
- An infection can result in damaged tissue that serves as a site for calculus development. Infected calculi (usually magnesium ammonium phosphate or staghorn calculi) may develop if bacteria serve as the nucleus in calculus formation. Such infections may promote destruction of renal parenchyma.
- Consistently acidic or alkaline urine provides a favorable medium for calculus formation.
- Urinary stasis (as in immobility from spinal cord injury) allows calculus constituents to collect and adhere, forming calculi. Obstruction also promotes infection which, in turn, compounds the obstruction.