Anticonvulsant Medications

Anticonvulsant Medications
• Anticonvulsant medications are used to depress abnormal neuronal discharges and prevent the spread of seizures to adjacent neurons.
• Anticonvulsant medications should be used with caution in clients taking anticoagulants, aspirin, sulfonamides, cimetidine (Tagamet), and antipsychotic drugs.
• Absorption is decreasedwith the use of antacids, calcium preparations, and antineoplastic medications.


Medication                                                    Therapeutic Serum Range
Amobarbital (Amytal)                                                        1-5 mcg/mL
Carbamazepine (Tegretol)                                                3-14 mcg/mL
Clonazepam (Klonopin)                                                     20-80 ng/mL
Ethosuximide (Zarontin)                                                    40-100 mcg/mL
Ethotoin (Peganone)                                                          10-50 mcg/mL
Lorazepam (Ativan)                                                             50-240 ng/mL
Mephobarbital (Mebaral)                                                 15-40 mcg/mL
Phenobarbital (Luminal)                                                   15-40 mcg/mL
Phenytoin (Dilantin)                                                          10-20 mcg/mL

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