Antiviral Agents Cheat Sheet

Viruses cause a variety of conditions, ranging from warts, to the common cold and “flu,” to diseases such as chickenpox and measles. A single virus particle is composed of a piece of DNA or RNA inside a protein coat.

 

Antiviral Agents

 

AGENTS FOR INFLUENZA A AND RESPIRATORY VIRUSES

  • amantadine
  • oseltamivir
  • ribavirin
  • rimantadine
  • zanamivir

AGENTS FOR HERPES VIRUS AND CYTOMEGALOVIRUS

  • acyclovir
  • cidofovir
  • famciclovir
  • foscarnet
  • ganciclovir
  • valacyclovir
  • valganciclovir

 

AGENTS FOR HIV AND AIDS

Nonnucleoside Reverse Transcriptase Inhibitors

  • delavirdine
  • efavirenz
  • nevirapine

Nucleoside Reverse Transcriptase Inhibitors

  • abacavir
  • didanosine
  • emtricitabine
  • lamivudine
  • stavudine
  • tenofovir
  • zalcitabine
  • zidovudine

 

Protease Inhibitors

  • atazanavir
  • fosamprenavir
  • indinavir
  • lopinavir
  • nelfinavir
  • ritonavir
  • saquinavir
  • tipranavir

 

Fusion Inhibitor

  • enfuvirtide

CCR5 Coreceptor

  • Antagonist
  • maraviroc

Integrase Inhibitor

  • raltegravir

ANTIHEPATITIS B AGENTS

  • adefovir
  • entecavir
  • telbivudine

LOCALLY ACTIVE ANTIVIRAL AGENTS

  • docosanol
  • ganciclovir
  • imiquimod
  • penciclovir
  • trifluridine

 

To carry on any metabolic processes, including replication, a virus must enter a cell. Once a virus has fused with a cell wall and injected its DNA or RNA into the host cell, that cell is altered—that is, it is “programmed” to control the metabolic processes that the virus needs to survive. The virus, including the protein coat, replicates in the host cell .

 

When the host cell can no longer carry out its own metabolic functions because of the viral invader, the host cell dies and releases the new viruses into the body to invade other cells.

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