NAPLEX Practice Question # 105


Practice Question # 105.


The traditional NSAIDs are structurally diverse group of molecules that are acids or acid prodrugs attached to a planar aromatic ring structure. Th e acidic functional group is responsible for binding to the same cationic site on COX bound by the natural substrate, arachidonic acid. The planar aromatic ring, generally one carbon from the acidic group, is analogous to the conjugated double bonds of arachidonic acid.

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