NAPLEX Practice Question # 17

NAPLEX Examination.

Take daily Practice Questions for the Naplex exam.


Naplex

 

 

Inotropic agents

  1. Have been used in the emergency treatment of patients with HF. However, long-term oral therapy with these agents has not improved symptoms or clinical status and has been reported to increase mortality, especially in patients with advanced HF.
  2. Th e current national guidelines provide a class IIb recommendation with a level C level of evidence for the use of intravenous inotropic drugs, such as dopamine (Various), dobutamine (Various), or milrinone (Various), as reasonable treatments for patients presenting to the hospital with documented severe systolic dysfunction, low blood pressure, and evidence of low cardiac output, with or without congestion, in order to maintain system perfusion and preserve end-organ performance.
  3. Th e current national guidelines also provide a class III recommendation with a level B level of evidence for the use of parenteral inotropic agents in normotensive patients in the hospitalized setting, with acute decompensated HF without evidence of decreased organ perfusion.
  4. Current national guidelines provide a class IIb recommendation with a level C for the use of continuous intravenous infusions of positive inotropic agents for palliation of symptoms in patients with refractory end-stage HF—stage D.
  5. Current national guidelines provide a class III recommendation with a level A level of evidence and states that the “routine intermittent infusions of vasoactive and positive inotropic agents are not recommended for patients with refractory end-stage HF—stage D.”

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