NAPLEX Examination.
Practice Question # 35.
Naplex
Pharmacotherapy options (antidepressants).
Pharmacotherapy can be used for mild to severe major depression and produces a response in 50% to 75% of patients. Some evidence suggests antidepressants are more eff ective in patients with moderate to severe depression. Antidepressants have similar effi cacy; however, they diff er in adverse eff ects, mechanism of action, drug–drug interactions, and cost.
Therefore, selection of an antidepressant should take these factors into consideration. Patients with a history of response to a particular agent may restart that agent if desired.
