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1. Question
In order to reduce toxicity with methotrexate, concomitant administration with what vitamin is recommended?
Correct
Answer & Explanation:
The answer is A
Explanation:
MTX inhibits dihydrofolate reductase. Research has shown supplemental doses of folic acid (e.g., 1 mg/day) can reduce side effects.
Incorrect
Answer & Explanation:
The answer is A
Explanation:
MTX inhibits dihydrofolate reductase. Research has shown supplemental doses of folic acid (e.g., 1 mg/day) can reduce side effects.
Methotrexate (MTX; Rheumatrex)
works by inhibiting dihydrofolate reductase and is considered standard therapy for RA. MTX is recommended for all patients with RA (as monotherapy or with other DMARDs) regardless of disease duration, disease burden, or prognostic factors. Concomitant use with folic acid may reduce side eff ects.