NAPLEX Practice Question # 97

NAPLEX Examination.

Practice Question # 97.


Naplex

 

The H1-receptor antagonists, or antihistamines, are divided into first- and second-generation agents based on the sedating activities of the agents secondary to CNS access and distribution.

(1) The classic, first-generation antihistamines include the chemical classes of

(a) the ethanolamines: carbinoxamine (Arbinoxa, Palgic), clemastine (Tavist), diphenhydramine (Benadryl), and doxylamine (Unisom);

(b) the alkylamines: brompheniramine (Dimetane, Brovex, Lodrane), chlorpheniramine (Chlor-Trimeton), dexbrompheniramine (Drixoral, Ala-Hist IR), dexchlorpheniramine (Polaramine), and triprolidine (Zymine, Actidil, Tripohist);

(c) the piperazine: hydroxyzine (Atarax, Vistaril);

(d) the piperidine: cyproheptadine (Periactin);

(e) the phenothiazine: promethazine (Phenergan).

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