NAPLEX Practice Question # 98

NAPLEX Examination.

Practice question # 98.


The PPIs covalently bind to the proton pump for an irreversible inhibition of acid secretion. The extensive and relatively long-term inhibition of gastric acid secretion is useful for the treatment of gastroesophageal reflux disease, duodenal ulcers, and makes PPIs the drugs of choice for Zollinger-Ellison syndrome. Several PPIs are marketed OTC for the treatment and prevention of heartburn.

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