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1. Question
Omeprazole would not be effective in the treatment of
Correct
Answer & Explanation:
The answer is E
Because choices A–D are all disease states that represent some action of excessive acid secretion, omeprazole, which also blocks the proton or acid pump, would be effective in reducing the acid-induced pain and damage associated with gastroesophageal refl ux disease (GERD), peptic ulcer disease (PUD), Zollinger- Ellison syndrome, and heartburn. Urticaria is best treated with a H1-receptor antagonist.
Incorrect
Answer & Explanation:
The answer is E
Because choices A–D are all disease states that represent some action of excessive acid secretion, omeprazole, which also blocks the proton or acid pump, would be effective in reducing the acid-induced pain and damage associated with gastroesophageal refl ux disease (GERD), peptic ulcer disease (PUD), Zollinger- Ellison syndrome, and heartburn. Urticaria is best treated with a H1-receptor antagonist.
The PPIs covalently bind to the proton pump for an irreversible inhibition of acid secretion. The extensive and relatively long-term inhibition of gastric acid secretion is useful for the treatment of gastroesophageal reflux disease, duodenal ulcers, and makes PPIs the drugs of choice for Zollinger-Ellison syndrome. Several PPIs are marketed OTC for the treatment and prevention of heartburn.