NCLEX RN Practice Question # 392


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Uses & Side effects of Reglan


  1. Medication: Metoclopramide (Reglan)
  2. Stimulates motility of the upper gastrointestinal tract and increases the rate of gastric emptying without stimulating gastric, biliary, or pancreatic secretions
  3. Used to treat gastroesophageal reflux and paralytic ileus
  4. May cause restlessness, drowsiness, extrapyramidal reactions, dizziness, insomnia, and headache
  5. Usually administered 30 minutes before meals and at bedtime
  6. Contraindicated in clients with sensitivity and in clients with mechanical obstruction, perforation, or gastrointestinal hemorrhage
  7. Can precipitate hypertensive crisis in clients with pheochromocytoma
  8. Safety in pregnancy is not established
  9. Metoclopramide (Reglan) can cause parkinsonian reactions; if this occurs, the medication will be discontinued by the physician.
  10. Anticholinergics and opioid analgesics antagonize the effects of metoclopramide.
  11. Alcohol, sedatives, cyclosporine (Sandimmune), and tranquilizers produce an additive effect.

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