NCLEX RN Practice Question # 392
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Uses & Side effects of Reglan
PROKINETIC AGENT
- Medication: Metoclopramide (Reglan)
- Stimulates motility of the upper gastrointestinal tract and increases the rate of gastric emptying without stimulating gastric, biliary, or pancreatic secretions
- Used to treat gastroesophageal reflux and paralytic ileus
- May cause restlessness, drowsiness, extrapyramidal reactions, dizziness, insomnia, and headache
- Usually administered 30 minutes before meals and at bedtime
- Contraindicated in clients with sensitivity and in clients with mechanical obstruction, perforation, or gastrointestinal hemorrhage
- Can precipitate hypertensive crisis in clients with pheochromocytoma
- Safety in pregnancy is not established
- Metoclopramide (Reglan) can cause parkinsonian reactions; if this occurs, the medication will be discontinued by the physician.
- Anticholinergics and opioid analgesics antagonize the effects of metoclopramide.
- Alcohol, sedatives, cyclosporine (Sandimmune), and tranquilizers produce an additive effect.