NCLEX RN Practice Question 455
Free NCLEX Practice Questions.
Take Practice Question # 455
Nclex free practice Questions.
MEDICATIONS FOR PREVENTING ORGAN REJECTION
Tacrolimus (Prograf)
- Tacrolimus inhibits calcineurin and thereby prevents T cells from producing interleukin-2, interferon- g, and other cytokines.
- Tacrolimus is more effective than cyclosporine, but is more toxic.
- Adverse effects are similar to those of cyclosporine and include nephrotoxicity, infection, hypertension, tremor, hirsutism, neurotoxicity, gastrointestinal effects, hyperkalemia, and hyperglycemia.
- Tacrolimus should be used cautiously in immunosuppressed clients and those with renal, hepatic, or pancreatic impairment.
- Tacrolimus is contraindicated for clients hypersensitive to cyclosporine.
- Monitor blood glucose levels and administer prescribed insulin or oral hypoglycemics.