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1. Question
Colchicine is prescribed for a client with a diagnosis of gout. The nurse reviews the client’s record, knowing that this medication would be used with caution in which disorder?
Correct
Answer: Option 2 is the correct answer.
Rationale: Colchicine is used with caution in older clients, debilitated clients, and clients with cardiac, kidney, or gastrointestinal disease. The disorders in options 1, 3, and 4 are not concerns with administration of this medication. Test-Taking Strategy: Focus on the subject, the cautions associated with colchicine. Note that options 1, 3, and 4 are comparable or alike and are endocrine-related disorders. The correct option is different from the others.
Incorrect
Answer: Option 2 is the correct answer.
Rationale: Colchicine is used with caution in older clients, debilitated clients, and clients with cardiac, kidney, or gastrointestinal disease. The disorders in options 1, 3, and 4 are not concerns with administration of this medication. Test-Taking Strategy: Focus on the subject, the cautions associated with colchicine. Note that options 1, 3, and 4 are comparable or alike and are endocrine-related disorders. The correct option is different from the others.
Colchicine:
Colchicine is used for acute attacks of gout and prophylactic prevention of gout. Good relief of pain. It is often effective in aborting an attack when taken at the first sign of articular discomfort.
Exact mechanism unknown. In patients with gout, may interrupt the cycle o monosodium urate crystal deposition in joint tissues and the resultant in lammatory response that initiates and sustains an acute attack. Colchicine also inhibits urate crystal deposition, which is enhanced by a low pH in the tissues, probably by inhibiting oxidation o glucose and subsequent lactic acid production in leukocytes.
