NCLEX RN Practice Question # 694

NCLEX Examination.

Practice Question # 694.



Aminoglycosides are bactericidal. They bind directly and irreversibly to 30S ribosomal subunits, inhibiting bacterial protein synthesis. They’re active against many aerobic gram-negative and some aerobic gram-positive organisms and can be used in combination with other antibiotics for short courses of therapy.

Adverse Reactions

Ototoxicity and nephrotoxicity are the most serious complications. Neuromuscular blockade also may occur. Oral forms most commonly cause diarrhea, nausea, and vomiting. Parenteral drugs may cause vein irritation, phlebitis, and sterile abscess.

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