Practice Question # 857.
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A burn client begins treatments with silver sulfadiazine (Silvadene) applied to the wounds. The nurse should carefully monitor for which adverse affect associated with this drug?Correct
Answer B is correct.
Rationale: A decreased WBC count can occur with the application of Silvadene. The nurse would need to assess the laboratory test results for this adverse effect. Decreased potassium, sodium, and platelets are not associated with Silvadene administration, which makes answers A, C, and D incorrect.Incorrect
Answer B is correct.
Rationale: A decreased WBC count can occur with the application of Silvadene. The nurse would need to assess the laboratory test results for this adverse effect. Decreased potassium, sodium, and platelets are not associated with Silvadene administration, which makes answers A, C, and D incorrect.
About silver sulfadiazine:
SILVADENE Cream 1% is a soft, white, water-miscible cream containing the antimicrobial agent silver sulfadiazine in micronized form, which has the following structural formula: Each gram of SILVADENE Cream 1% contains 10 mg of micronized silver sulfadiazine. The cream vehicle consists of white petrolatum, stearyl alcohol, isopropyl myristate, sorbitan monooleate, polyoxyl 40 stearate, propylene glycol, and water, with methylparaben 0.3% as a preservative. SILVADENE Cream 1% (silver sulfadiazine) spreads easily and can be washed off readily with water.
Silver sulfadiazine has broad antimicrobial activity. It is bactericidal for many gram-negative and gram-positive bacteria as well as being effective against yeast. Results from in vitro testing are listed below. Sufficient data have been obtained to demonstrate that silver sulfadiazine will inhibit bacteria that are resistant to other antimicrobial agents and that the compound is superior to sulfadiazine. Studies utilizing radioactive micronized silver sulfadiazine, electron microscopy, and biochemical techniques have revealed that the mechanism of action of silver sulfadiazine on bacteria differs from silver nitrate and sodium sulfadiazine. Silver sulfadiazine acts only on the cell membrane and cell wall to produce its bactericidal effect.