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1. Question
A client is to begin a 6-month course of therapy with isoniazid. The nurse should plan to teach the client to take which action?
Correct
Option 2 is the correct answer:
Rationale:Isoniazid is hepatotoxic, and therefore the client is taught to report signs and symptoms of hepatitis immediately, which include yellow skin and sclera. For the same reason, alcohol should be avoided during therapy. The client should avoid intake of Swiss cheese, fish such as tuna, and foods containing tyramine, because they may cause a reaction characterized by redness and itching of the skin, flushing, sweating, tachycardia, headache, or lightheadedness. The client can avoid developing peripheral neuritis by increasing the intake of pyridoxine (vitamin B6) during the course of isoniazid therapy.
Incorrect
Option 2 is the correct answer:
Rationale:Isoniazid is hepatotoxic, and therefore the client is taught to report signs and symptoms of hepatitis immediately, which include yellow skin and sclera. For the same reason, alcohol should be avoided during therapy. The client should avoid intake of Swiss cheese, fish such as tuna, and foods containing tyramine, because they may cause a reaction characterized by redness and itching of the skin, flushing, sweating, tachycardia, headache, or lightheadedness. The client can avoid developing peripheral neuritis by increasing the intake of pyridoxine (vitamin B6) during the course of isoniazid therapy.
Isoniazid Introduction:
Indications: Treatment of tuberculosis as part of combination therapy; prophylactic treatment of household members of recently diagnosed tuberculars.
Actions: Interferes with lipid and nucleic acid synthesis in actively growing tubercle bacilli.
Adverse effects: Peripheral neuropathies, nausea, vomiting, hepatitis, bone marrow suppression, fever, local irritation at injection sites, gynecomastia, lupus syndrome.
